As per your chart, you would have quite high level of expenses to manage, it would be prudent for you to manage your expenses.
The current time is good for you to start your business till Dec 2022. Thereafter again you have a favourable time from Feb 2024 onwards when you have a good time to prosper in a business environment and also free from most kind of troubles.
Yes, as per your chart you can start your business again and have decent earnings, however you need to keep your expenses under control.
Mesha lagna with the lagna lord Mars posited in the fifth house; Tenth lord retrograde Saturn posited in the tenth house; Ketu posited in the ninth house and Venus posited in the second house in own sign.
Ketu Maha Dasha ongoing currently with Jupiter Antar Dasha till Dec 2022 and Mercury Maha Dasha starts from Feb 2024 onwards and Venus Maha Dasha starts from Feb 2025.